Confidence in all stages of treponemal infection
- Syphilis is caused by the intracellular Gram-negative spirochete bacterium Treponema pallidum subspecies pallidum
- In 2012, approximately 12 million new cases of infection were reported.
- Most people with syphilis are asymptomatic, but if untreated the infection can cause significant complications.
- Although syphilis is usually transmitted sexually, it can also be transmitted from mother to fetus with an estimated 1.5 million pregnancies affected globally each year. However, if diagnosed in the early stages, syphilis can be successfully treated and congenital syphilis prevented.
- Syphilis can be transmitted through blood transfusions.
- Serological tests like the Elecsys Syphilis assay are the method of choice for the reliable detection of Treponema palladium infections.
Featured Article: Syphilis is returning
||Assay detects total IgG and IgM against bacterial TpN15, TpN17, TpN47
||Serum, Li-heparin, K2- and K3-EDTA, sodium citrate and CPDA plasma
||cobas e 411 analyzer, Elecsys ™ 2010 analyzer
cobas e 601/e 602 modules, Modular™ ANALYTICS <E 170>
||99.93% (n=4579 blood donors)
99.80% (n=3500 unselected routine samples)
||>200 samples containing antibodies against different pathogens showed no cross reactivity
Source: Data on file
Designed for high sensitivity and specificity
- High sensitivity and specificity minimizes the probability of missing true positives in all stages of infection
Clear interpretation of results
- Clear cut-off separation of positive and negative results
Efficient use of sample volume and time
- Only 10uL testing volume allows to perform all tests using the same sample
- Result obtained in only 18 minutes
Efficiency for diagnostic use and blood donor screening
- Fully automated and integrated with other tests in the STD, TORCH and Blood Safety portfolios